Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.41 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994636 | 1.00 | RAB9A (0.46) | RAB9ANPC1KDM4EMAPTJUN | |
| SCHEMBL6166697 | 0.84 | CYP1A1 (0.58) | RAB9AKDM4EMAPTMAPK1ALDH1A1 | |
| SCHEMBL6166690 | 0.84 | CYP1A1 (0.58) | RAB9AKDM4EMAPTMAPK1ALDH1A1 | |
| SCHEMBL6140546 | 0.83 | APP (0.56) | KDM4EMAPTJUNNFKB1MAPK1 | |
| SCHEMBL6140549 | 0.83 | APP (0.56) | KDM4EMAPTJUNNFKB1MAPK1 | |
| SCHEMBL6166947 | 0.80 | CYP1A1 (0.53) | RAB9ANPC1KDM4EMAPTJUN | |
| SCHEMBL6166941 | 0.80 | CYP1A1 (0.53) | RAB9ANPC1KDM4EMAPTJUN | |
| Hydrochloric Acid SCHEMBL6166154 | 0.79 | CYP1A1 (0.52) | RAB9ANPC1KDM4EMAPTJUN | |
| Hydrochloric Acid SCHEMBL6166145 | 0.79 | CYP1A1 (0.52) | RAB9ANPC1KDM4EMAPTJUN | |
| SCHEMBL21895554 | 0.75 | RAB9A (0.51) | RAB9ANPC1KDM4EMAPTJUN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313153-B1 | ADMINISTERING PYRIDYLACRYLAMIDE COMPOUND FOR THERAPY OF NEPHRITIS | TSUMURA & CO. (JP) | 2001-11-06 | — | — | US | disclosed |
| EP-1000935-A1 | PYRIDYLACRYLAMIDE DERIVATIVES AND NEPHRITIS REMEDIES AND TGF-$g(b) INHIBITORS CONTAINING THE SAME | TSUMURA & CO. (JP) | 2000-05-17 | — | — | EP | disclosed |