Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.56 |
| ▸ | IAPP | P10997 | 4/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | TTR | P02766 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140549 | 1.00 | APP (0.56) | APPIAPPPTGS1MMP1MMP2 | |
| SCHEMBL7994636 | 0.83 | RAB9A (0.46) | APPKDM4EMAPTTDP1POLB | |
| SCHEMBL7994633 | 0.83 | RAB9A (0.46) | APPKDM4EMAPTTDP1POLB | |
| SCHEMBL30364339 | 0.80 | HIF1A (0.50) | IAPPPTGS1KDM4EMAPTTDP1 | |
| SCHEMBL4878047 | 0.78 | APP (0.62) | APPKDM4EMAPTHSD17B10HPGD | |
| SCHEMBL4878055 | 0.78 | APP (0.62) | APPKDM4EMAPTHSD17B10HPGD | |
| SCHEMBL26038107 | 0.78 | IAPP (0.66) | APPIAPPPTGS1MMP1MMP2 | |
| SCHEMBL8848008 | 0.77 | IAPP (0.67) | APPIAPPPTGS1MMP1MMP2 | |
| SCHEMBL9683152 | 0.77 | IAPP (0.67) | APPIAPPPTGS1MMP1MMP2 | |
| SCHEMBL4885116 | 0.76 | TRPM8 (0.62) | KDM4EMAPTHPGDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1646480-A | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | MOGAM BIOTECH RES INST (KR) | 2005-07-27 | — | — | CN | claimed |
| US-20040082664-A1 | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2004-04-29 | — | — | US | claimed |
| WO-2005072723-A1 | PHARMACEUTICAL COMPOSITION COMPRISING HYDROXYLPHENYL DERIVATIVES OF ROSMARINIC ACID FOR ANTICANCER | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2005-08-11 | — | — | WO | disclosed |
| CN-1646480-A | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | MOGAM BIOTECH RES INST (KR) | 2005-07-27 | — | — | CN | disclosed |
| EP-1499585-A1 | DERIVATIVES OF HYDROXYPHENYL, A METHOD FOR PREPARING THEREOF AND THEIR PHARMACEUTICAL COMPOSITION | Mogam Biotechnology Research Institute (KR) | 2005-01-26 | — | — | EP | disclosed |
| US-20040082664-A1 | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2004-04-29 | — | — | US | disclosed |
| WO-2003089405-A1 | DERIVATIVES OF HYDROXYPHENYL, A METHOD FOR PREPARING THEREOF AND THEIR PHARMACEUTICAL COMPOSITION | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2003-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082664-A1 | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | LCK, SRC, FYN | APP 2764/4885IAPP 1162/4885PTGS1 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.