Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984159 | 0.90 | EGFR (0.31) | — | |
| SCHEMBL7994645 | 0.88 | HSP90AA1 (0.34) | — | |
| SCHEMBL7998616 | 0.82 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL7998777 | 0.78 | GRM2 (0.45) | CYP2D6TSHRCYP2C19HIF1AGRM2 | |
| SCHEMBL7994182 | 0.76 | KMT2A (0.40) | CYP2D6TSHRCYP2C19HIF1AGRM2 | |
| SCHEMBL8081077 | 0.75 | CYP1A2 (0.33) | TSHRGRM2 | |
| SCHEMBL8001628 | 0.74 | GRM2 (0.41) | CYP2D6GRM2 | |
| SCHEMBL7994719 | 0.73 | HTR7 (0.34) | CYP2D6TSHRCYP2C19HIF1AGRM2 | |
| SCHEMBL7996539 | 0.71 | TP53 (0.41) | — | |
| SCHEMBL7994819 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |