Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998420 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TDP1TYMSCYP3A4HSD17B10 | |
| SCHEMBL27818709 | 0.83 | ALDH1A1 (0.57) | ALDH1A1TDP1TYMSCYP3A4HSD17B10 | |
| SCHEMBL1274665 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TDP1TYMSCYP3A4HSD17B10 | |
| SCHEMBL8927887 | 0.80 | TDP1 (0.59) | ALDH1A1TDP1CYP3A4HSD17B10ALOX15 | |
| SCHEMBL2043406 | 0.78 | ALDH1A1 (0.62) | ALDH1A1TDP1TYMSCYP3A4HSD17B10 | |
| SCHEMBL7994729 | 0.78 | ALDH1A1 (0.46) | ALDH1A1TDP1TYMSCYP3A4HSD17B10 | |
| 1-Nitropyrene SCHEMBL339725 | 0.77 | ALDH1A1 (0.57) | ALDH1A1TDP1CYP3A4HSD17B10HPRT1 | |
| 1-Nitropyrene SCHEMBL29450697 | 0.77 | ALDH1A1 (0.57) | ALDH1A1TDP1CYP3A4HSD17B10HPRT1 | |
| SCHEMBL15835264 | 0.76 | ALDH1A1 (0.45) | ALDH1A1TDP1TYMSCYP3A4HSD17B10 | |
| SCHEMBL14115813 | 0.76 | TDP1 (0.42) | ALDH1A1TDP1TYMSCYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294380-B1 | Liver cell clones for use in extracorporeal liver-assist device | JMS CO., LTD. (JP) | 2001-09-25 | — | — | US | disclosed |
| EP-1063289-A1 | Liver cell clones for artifical liver and extracorporeal liver assist device | JMS Co., Ltd. (JP) | 2000-12-27 | — | — | EP | disclosed |