Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11854289 | 0.98 | LTA4H (0.54) | LTA4HKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL10828180 | 0.93 | LTA4H (0.68) | LTA4HKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL19760406 | 0.87 | LTA4H (0.54) | LTA4HKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL10829140 | 0.87 | GAA (0.62) | LTA4HKDM4ELMNA | |
| SCHEMBL10829172 | 0.87 | LTA4H (0.69) | LTA4HMEN1KMT2A | |
| SCHEMBL11854284 | 0.86 | LTA4H (0.53) | LTA4HKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL21595690 | 0.86 | DRD2 (0.60) | KDM4ESMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL2476605 | 0.86 | KDM4E (0.49) | LTA4HKDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL21595882 | 0.84 | HRH3 (0.58) | KDM4ESMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL21595960 | 0.84 | KDM4E (0.68) | LTA4HKDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019244066-A2 | PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2019-12-26 | — | — | WO | disclosed |
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | disclosed |
| WO-1999061251-A1 | THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-02 | — | — | WO | disclosed |