Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668749 | 0.84 | OPRM1 (0.48) | OPRM1ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL7702085 | 0.83 | OPRM1 (0.47) | OPRM1ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL7664127 | 0.83 | OPRM1 (0.47) | OPRM1ADRA1AADRA1DADRA1B | |
| SCHEMBL8010117 | 0.82 | ADRA1A (0.47) | OPRM1ADRA1AADRA1DADRA1B | |
| SCHEMBL7668741 | 0.81 | ADRA1A (0.44) | OPRM1ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL7664114 | 0.80 | ADRA1A (0.44) | OPRM1ADRA1AADRA1DADRA1B | |
| SCHEMBL7840973 | 0.80 | OPRM1 (0.66) | OPRM1OPRD1ADRA1AOPRL1ADRA1D | |
| SCHEMBL10526389 | 0.78 | TSHR (0.40) | OPRM1ADRA1A | |
| SCHEMBL30410927 | 0.78 | TSHR (0.40) | OPRM1ADRA1A | |
| SCHEMBL17434404 | 0.75 | NPC1 (0.38) | OPRM1ADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000025782-A1 | DIHYDROPYRIDINONES AND PYRROLINONES USEFUL AS ALPHA 1A ADRENOCEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | claimed |
| WO-2000025782-A1 | DIHYDROPYRIDINONES AND PYRROLINONES USEFUL AS ALPHA 1A ADRENOCEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |