Sulfuric Acid

Sulfuric Acid

SCHEMBL7994836

O=S(=O)(O)O.OCc1cc2ccccc2c2ccc3ccccc3c12

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA known ✓ P21397 1/20 0.43
ERBB2 P04626 1/20 0.43
CYP1A2 P05177 1/20 0.43
FYN P06241 1/20 0.43
ACHE P22303 1/20 0.43
AHR P35869 1/20 0.43
ALDH1A1 P00352 3/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 2/20 0.42
HIF1A Q16665 1/20 0.42
CYP1B1 Q16678 1/20 0.42
HPRT1 P00492 2/20 0.41
CYP2A6 P11509 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA9 Q16790 1/20 0.39
AKR1B1 P15121 1/20 0.38
MPL P40238 1/20 0.38
CTRC Q99895 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4630262 0.92 ALDH1A1 (0.50) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL7994830 0.82 CYP1A2 (0.39) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL2314306 0.80 CYP1A2 (0.46) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL7794322 0.80 CYP1A2 (0.48) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL18179348 0.78 TRPM4 (0.43) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL17183137 0.78 HSD17B10 (0.50) ERBB2CYP1A2FYNMAOAACHE
Sulfuric Acid SCHEMBL438828 0.73 ALDH1A1 (0.65) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL17183186 0.72 CYP1A2 (0.44) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL2313421 0.72 CYP1A2 (0.41) ERBB2CYP1A2FYNMAOAACHE
SCHEMBL25368551 0.71 CYP1B1 (0.41) ERBB2CYP1A2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6294380-B1 Liver cell clones for use in extracorporeal liver-assist device JMS CO., LTD. (JP) 2001-09-25 US disclosed
EP-1063289-A1 Liver cell clones for artifical liver and extracorporeal liver assist device JMS Co., Ltd. (JP) 2000-12-27 EP disclosed