Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996560 | 0.89 | L3MBTL1 (0.57) | L3MBTL1TSHRALDH1A1LMNANPC1 | |
| SCHEMBL9084932 | 0.89 | TSHR (0.53) | L3MBTL1TSHRALDH1A1LMNANPC1 | |
| Acetone SCHEMBL9090087 | 0.83 | TSHR (0.49) | L3MBTL1TSHRALDH1A1LMNANPC1 | |
| SCHEMBL9085242 | 0.83 | TSHR (0.47) | L3MBTL1TSHRALDH1A1LMNANPC1 | |
| SCHEMBL9082785 | 0.76 | RAF1 (0.44) | L3MBTL1TSHRALDH1A1LMNANPC1 | |
| SCHEMBL10064723 | 0.74 | TSHR (0.56) | L3MBTL1TSHRALDH1A1LMNANPC1 | |
| SCHEMBL7994849 | 0.73 | EPHX2 (0.50) | L3MBTL1TSHRALDH1A1LMNANPC1 | |
| Hydrochloric Acid SCHEMBL7984877 | 0.72 | EPHX2 (0.49) | L3MBTL1TSHRALDH1A1LMNANPC1 | |
| SCHEMBL9084428 | 0.71 | TSHR (0.38) | L3MBTL1TSHRALDH1A1LMNANPC1 | |
| SCHEMBL7994913 | 0.71 | L3MBTL1 (0.43) | L3MBTL1TSHRALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074789-A1 | NEW (1-ADAMANTYLAMINO)PYRIMIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | claimed |
| WO-2001074789-A1 | NEW (1-ADAMANTYLAMINO)PYRIMIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | disclosed |