Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7984877 | 0.98 | EPHX2 (0.49) | EPHX2KDM4EL3MBTL1TSHRALDH1A1 | |
| SCHEMBL7996560 | 0.80 | L3MBTL1 (0.57) | EPHX2L3MBTL1TSHRALDH1A1LMNA | |
| SCHEMBL7984822 | 0.77 | EPHX2 (0.57) | EPHX2KDM4EL3MBTL1TSHRALDH1A1 | |
| SCHEMBL2568568 | 0.75 | HRH4 (0.59) | TSHRALDH1A1HSD17B10 | |
| SCHEMBL7994986 | 0.73 | L3MBTL1 (0.50) | EPHX2L3MBTL1TSHRALDH1A1LMNA | |
| SCHEMBL7977522 | 0.72 | NPC1 (0.46) | EPHX2L3MBTL1TSHRALDH1A1LMNA | |
| SCHEMBL7967024 | 0.71 | ALDH1A1 (0.59) | EPHX2KDM4EL3MBTL1TSHRALDH1A1 | |
| SCHEMBL30594845 | 0.69 | GABBR2 (0.41) | EPHX2KDM4EL3MBTL1TSHRALDH1A1 | |
| SCHEMBL14859316 | 0.69 | GABBR2 (0.41) | EPHX2KDM4EL3MBTL1TSHRALDH1A1 | |
| SCHEMBL9164607 | 0.68 | HDAC3 (0.49) | EPHX2L3MBTL1TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074789-A1 | NEW (1-ADAMANTYLAMINO)PYRIMIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | claimed |
| WO-2001074789-A1 | NEW (1-ADAMANTYLAMINO)PYRIMIDINES AND METHOD OF THEIR PREPARATION | FUNDACJA ROZWOJU DIAGNOSTYKI I TERAPII (PL) | 2001-10-11 | — | — | WO | disclosed |