Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | SLC2A1 | P11166 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.54 |
| ▸ | TSPO | P30536 | 2/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431867 | 0.86 | ALDH1A1 (0.63) | ALDH1A1SLC2A1MEN1KMT2AKDM4E | |
| SCHEMBL1430434 | 0.83 | KDM4E (0.64) | SLC2A1KDM4EHTTGABRB2 | |
| Hydrochloric Acid SCHEMBL1429987 | 0.81 | ALDH1A1 (0.68) | ALDH1A1SLC2A1MEN1KMT2AKDM4E | |
| SCHEMBL1691241 | 0.81 | ALDH1A1 (0.68) | ALDH1A1SLC2A1MEN1KMT2AKDM4E | |
| SCHEMBL2775807 | 0.80 | GABRA1 (0.57) | ALDH1A1SLC2A1KDM4EHTTGABRA2 | |
| SCHEMBL11016012 | 0.79 | GAA (0.52) | ALDH1A1SLC2A1MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL1430569 | 0.79 | ALDH1A1 (0.54) | ALDH1A1SLC2A1MEN1KMT2AKDM4E | |
| SCHEMBL11013527 | 0.78 | GAA (0.51) | ALDH1A1SLC2A1MEN1KMT2AKDM4E | |
| SCHEMBL13368336 | 0.77 | ALDH1A1 (0.63) | ALDH1A1SLC2A1MEN1KMT2AKDM4E | |
| SCHEMBL2195258 | 0.77 | SLC2A1 (0.66) | ALDH1A1SLC2A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460592-A | HYPNOTIC | SYNTHELABO | 1984-07-17 | — | — | US | disclosed |
| US-4382938-A | HYPNOSIS; TENSION; ANTICONVULSANTS; PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | SYNTHELABO (FR) | 1983-05-10 | — | — | US | disclosed |