Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991473 | 0.92 | NPC1 (0.70) | NPC1RAB9ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL7994813 | 0.86 | NPSR1 (0.80) | NPC1RAB9ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL7980668 | 0.86 | MEN1 (0.60) | NPC1RAB9ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL7992207 | 0.84 | RAB9A (0.63) | NPC1RAB9ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL7994779 | 0.83 | NPC1 (0.80) | NPC1RAB9ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL8655167 | 0.82 | NPC1 (0.55) | NPC1RAB9ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL7995865 | 0.81 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7998271 | 0.81 | NPSR1 (0.56) | NPC1RAB9ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL7980732 | 0.80 | NPC1 (0.80) | NPC1RAB9ANPSR1SMN1; SMN2TSHR | |
| SCHEMBL7992723 | 0.78 | NPC1 (0.53) | NPC1RAB9ANPSR1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | claimed |
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | disclosed |
| WO-1999061251-A1 | THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-02 | — | — | WO | disclosed |