Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.80 |
| ▸ | RAB9A | P51151 | 6/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.80 |
| ▸ | TSHR | P16473 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980732 | 0.94 | NPC1 (0.80) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7995865 | 0.92 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL4076346 | 0.89 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7991486 | 0.86 | KCNA5 (0.61) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7994882 | 0.85 | NPC1 (0.80) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL17342583 | 0.85 | NPC1 (0.80) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7980693 | 0.84 | NPC1 (0.60) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7995034 | 0.83 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL7995040 | 0.83 | RAB9A (0.76) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL8655167 | 0.82 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | claimed |
| US-6294502-B1 | Thermally-responsive record material | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-25 | — | — | US | disclosed |