SCHEMBL7998271

SCHEMBL7998271

Cc1cccc(NC(=O)OCCOc2ccccc2Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.56
MEN1 O00255 6/20 0.56
KMT2A Q03164 6/20 0.56
NPC1 O15118 5/20 0.56
RAB9A P51151 5/20 0.56
MAPT P10636 3/20 0.49
HPGD P15428 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
TSHR P16473 2/20 0.49
MAPK1 P28482 3/20 0.48
ALDH1A1 P00352 2/20 0.48
FAAH O00519 1/20 0.48
CYP3A4 P08684 1/20 0.48
HTT P42858 2/20 0.47
GAA P10253 1/20 0.47
THRB P10828 1/20 0.47
ALOX12 P18054 1/20 0.47
LMNA P02545 4/20 0.47
TP53 P04637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7992735 0.88 MEN1 (0.62) NPSR1MEN1KMT2ANPC1RAB9A
SCHEMBL7980980 0.88 NPSR1 (0.59) NPSR1MEN1KMT2ANPC1RAB9A
SCHEMBL7992789 0.86 NPSR1 (0.76) NPSR1MEN1KMT2ANPC1RAB9A
SCHEMBL7991473 0.86 NPC1 (0.70) NPSR1MEN1KMT2ANPC1RAB9A
SCHEMBL7980666 0.82 RAB9A (0.74) NPSR1MEN1KMT2ANPC1RAB9A
SCHEMBL7992723 0.81 NPC1 (0.53) NPSR1MEN1KMT2ANPC1RAB9A
SCHEMBL7995034 0.81 NPC1 (0.59) NPSR1MEN1KMT2ANPC1RAB9A
SCHEMBL7980860 0.81 NPC1 (0.62) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL7991544 0.80 TP53 (0.61) MEN1KMT2ANPC1RAB9AHPGD
SCHEMBL10192012 0.79 HPGD (0.56) MEN1KMT2ANPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6294502-B1 Thermally-responsive record material BAYER AKTIENGESELLSCHAFT (DE) 2001-09-25 US claimed
US-6294502-B1 Thermally-responsive record material BAYER AKTIENGESELLSCHAFT (DE) 2001-09-25 US disclosed
WO-1999061251-A1 THERMALLY-RESPONSIVE RECORD MATERIAL CONTAINING A CARBAMATE COMPONENT BAYER AKTIENGESELLSCHAFT (DE) 1999-12-02 WO disclosed