Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6593121 | 0.72 | AVPR1A (0.53) | ALDH1A1KDM4EHPGDAPPPTGS2 | |
| SCHEMBL1450230 | 0.69 | F3 (0.52) | HDAC1HDAC8HDAC6HDAC10HDAC2 | |
| SCHEMBL1124325 | 0.68 | MAPT (0.62) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL1124327 | 0.68 | MAPT (0.62) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL7990776 | 0.65 | CYP11B1 (0.55) | HDAC1HDAC8HDAC6HDAC10HDAC2 | |
| SCHEMBL7990780 | 0.65 | CYP11B1 (0.55) | HDAC1HDAC8HDAC6HDAC10HDAC2 | |
| Benzene SCHEMBL28260361 | 0.65 | MAPT (0.62) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL22724123 | 0.65 | RAB9A (0.43) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL10521756 | 0.64 | MAPT (0.56) | ALDH1A1KDM4ENPC1HPGDRAB9A | |
| SCHEMBL13067872 | 0.64 | MAPT (0.56) | ALDH1A1KDM4ENPC1HPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009112-A1 | NOVEL 8-CARBONYL CHROMAN DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | AVENTIS PHARMA S.A. (FR) | 2001-02-08 | — | — | WO | disclosed |