Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6184665 | 0.90 | ALDH1A1 (0.37) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| Water SCHEMBL10748471 | 0.87 | TSHR (0.44) | TSHRCASP1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL30513966 | 0.80 | ALDH1A1 (0.61) | TSHRCASP1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL1697502 | 0.80 | SMN1; SMN2 (0.61) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL11681042 | 0.80 | ALDH1A1 (0.61) | TSHRCASP1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL30513965 | 0.80 | SMN1; SMN2 (0.61) | TSHRCASP1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL7312809 | 0.78 | GUSB (0.47) | ALDH1A1KMT2ATP53CA12CA1 | |
| SCHEMBL27637606 | 0.77 | JAK2 (0.47) | TSHRCASP1SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL293634 | 0.73 | CES2 (0.60) | TSHRALDH1A1MAPK1TDP1KMT2A | |
| SCHEMBL29952517 | 0.73 | CES2 (0.60) | TSHRALDH1A1MAPK1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017997-A1 | SUBSTITUTED DIAZAANTHRACENE COMPOUNDS HAVING PHARMACEUTICAL UTILITY | DIAZANS LIMITED (CA) | 2001-03-15 | — | — | WO | disclosed |
| US-5994365-A | BACTERICIDES; FUNGICIDES; ANTITUMOR AGENT | DIAZANS LIMITED (CA) | 1999-11-30 | — | — | US | disclosed |