Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30513965 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2TSHRCASP1MAPTALDH1A1 | |
| SCHEMBL30513966 | 0.83 | ALDH1A1 (0.61) | SMN1; SMN2TSHRCASP1ALDH1A1KDM4E | |
| SCHEMBL11681042 | 0.83 | ALDH1A1 (0.61) | SMN1; SMN2TSHRCASP1ALDH1A1KDM4E | |
| SCHEMBL1349424 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRCASP1MAPTALDH1A1 | |
| SCHEMBL2771192 | 0.81 | MAPT (0.44) | SMN1; SMN2TSHRCASP1MAPTALDH1A1 | |
| SCHEMBL10999586 | 0.80 | ALDH1A1 (0.63) | SMN1; SMN2TSHRCASP1MAPTALDH1A1 | |
| SCHEMBL27637606 | 0.80 | JAK2 (0.47) | SMN1; SMN2TSHRCASP1MAPTALDH1A1 | |
| SCHEMBL11241838 | 0.80 | RAB9A (0.58) | SMN1; SMN2TSHRCASP1MAPTALDH1A1 | |
| SCHEMBL11241833 | 0.80 | RAB9A (0.58) | SMN1; SMN2TSHRCASP1MAPTALDH1A1 | |
| SCHEMBL7995109 | 0.80 | TSHR (0.38) | SMN1; SMN2TSHRCASP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496151-A | Method for preparing fluorenone derivative by using Catellani strategy | 长沙医学院 | 2023-07-28 | — | — | CN | disclosed |
| EP-2609067-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ESTER | Sumitomo Chemical Co., Ltd (JP) | 2013-07-03 | — | — | EP | disclosed |
| US-20130150611-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-13 | — | — | US | disclosed |
| US-20130109884-A1 | PROCESS FOR PRODUCING ALPHA-KETOCARBOXYLIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-02 | — | — | US | disclosed |
| EP-2585427-A1 | PROCESS FOR PRODUCING ALPHA-KETOCARBOXYLIC ACID | Sumitomo Chemical Company Limited (JP) | 2013-05-01 | — | — | EP | disclosed |
| WO-2013018626-A1 | METHOD FOR PRODUCING ALPHA-KETOALDEHYDE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-07 | — | — | WO | disclosed |
| WO-2012176930-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-12-27 | — | — | WO | disclosed |
| WO-2012026617-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | WO | disclosed |
| WO-2011162404-A1 | PROCESS FOR PRODUCING ALPHA-KETOCARBOXYLIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-29 | — | — | WO | disclosed |
| EP-0204172-B1 | PHENYLPYRAZINE DERIVATIVES, PROCESSES FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION AND USE | SUNTORY LIMITED (JP) | 1990-09-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109884-A1 | PROCESS FOR PRODUCING ALPHA-KETOCARBOXYLIC ACID | ALDH18A1, MCCC2, ALDH7A1 | SMN1; SMN2 4535/4885TSHR 4683/4885CASP1 338/4885 |
| US-20130150611-A1 | PROCESS FOR PRODUCING CARBOXYLIC ACID ESTER | ADH5, ADH1A, ADH1C | SMN1; SMN2 2974/4885TSHR 975/4885CASP1 3490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.