Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 11/20 | 0.49 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998567 | 0.83 | HSD11B1 (0.62) | HSD11B1 | |
| SCHEMBL7980917 | 0.81 | GLA (0.49) | HSD11B1 | |
| SCHEMBL2056490 | 0.80 | HSD11B1 (0.46) | HSD11B1 | |
| SCHEMBL7980912 | 0.80 | HSD11B1 (0.67) | HSD11B1KDM4E | |
| SCHEMBL7989134 | 0.78 | HSD11B1 (0.46) | HSD11B1HSD11B2 | |
| SCHEMBL12677376 | 0.76 | HSD11B1 (0.50) | HSD11B1HSD11B2 | |
| SCHEMBL12677424 | 0.75 | HSD11B1 (0.47) | HSD11B1HSD11B2 | |
| SCHEMBL7968569 | 0.75 | HSD11B1 (0.46) | HSD11B1HSD11B2 | |
| SCHEMBL7980060 | 0.74 | HSD11B1 (0.45) | HSD11B1HSD11B2 | |
| SCHEMBL7982162 | 0.70 | NOTUM (0.43) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |