Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080801 | 1.00 | FDPS (0.51) | FDPSKDM4ENAPRTCYP1A2CYP2D6 | |
| SCHEMBL8476898 | 0.83 | CHRNA7 (0.49) | KDM4ENAPRTCYP1A2CYP2D6CHRNA7 | |
| SCHEMBL200084 | 0.82 | FDPS (0.51) | FDPSKDM4ENAPRTCYP1A2CYP2D6 | |
| SCHEMBL9426152 | 0.79 | FDPS (0.49) | FDPSKDM4ENAPRTCYP1A2CYP2D6 | |
| SCHEMBL9547411 | 0.79 | FDPS (0.59) | FDPSKDM4ENAPRTCYP1A2CYP2D6 | |
| SCHEMBL9793910 | 0.77 | MAOB (0.47) | KDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL134502 | 0.77 | MAOB (0.47) | KDM4ECYP1A2CYP2D6CYP3A4 | |
| SCHEMBL4726907 | 0.76 | FDPS (0.56) | FDPSKDM4ENAPRTCYP1A2CYP2D6 | |
| SCHEMBL12632304 | 0.76 | FDPS (0.56) | FDPSKDM4ENAPRTCYP1A2CYP2D6 | |
| SCHEMBL14828666 | 0.76 | FDPS (0.56) | FDPSKDM4ENAPRTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107298-A | ADMINISTERING AN AMINE SUBSTITUTED PYRIMIDINE OR PYRIDINE COMPOUND | BENCHERIF MEROUANE (US) | 2000-08-22 | — | — | US | disclosed |