SCHEMBL134502

SCHEMBL134502

C#CC(O)Cc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.47
CYP1A2 P05177 4/20 0.46
TSHR P16473 3/20 0.46
CYP2D6 P10635 2/20 0.46
CYP3A4 P08684 1/20 0.46
EPHX1 P07099 1/20 0.44
TRPA1 O75762 2/20 0.44
MAOA P21397 5/20 0.43
PKM P14618 2/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
ADRA1A P35348 1/20 0.43
SNCA P37840 1/20 0.43
OPRK1 P41145 1/20 0.43
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42
SLC1A1 P43005 1/20 0.42
ALPI P09923 1/20 0.42
PTGS1 P23219 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9793910 1.00 MAOB (0.47) MAOBCYP1A2TSHRCYP2D6CYP3A4
SCHEMBL9349134 0.83 LTA4H (0.52)
SCHEMBL10871643 0.79 PPARG (0.48) TSHRPTGS1
SCHEMBL817399 0.78 ANPEP (0.43) TSHRCYP2D6CYP3A4GAANPBWR1
SCHEMBL8842181 0.78 MAOA (0.46) MAOBTRPA1MAOATAAR1
SCHEMBL817464 0.78 ANPEP (0.43) TSHRCYP2D6CYP3A4GAANPBWR1
SCHEMBL20488218 0.78 SLC6A4 (0.48) CYP1A2CYP2D6GAAKMT2ASLC6A2
SCHEMBL28634122 0.78 PYCR1 (0.40) CYP1A2ADRA1AKMT2ATAAR1
SCHEMBL28720952 0.78 PYCR1 (0.44) MAOBTAAR1
SCHEMBL6334251 0.77 TSHR (0.46) MAOBCYP1A2TSHREPHX1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114921220-A Pressure-sensitive adhesive and protective film suitable for polylactic acid resin base material and preparation method thereof 惠州市浩明科技股份有限公司 2022-08-19 CN claimed
CN-105504825-B Silicone rubber composition and method for producing same 现代摩比斯株式会社 2021-01-08 CN claimed
EP-2142552-B1 INHIBITORS OF DIACYLGLYCEROL O-ACYLTRANSFERASE TYPE 1 ENZYME ABBOTT LAB (US) 2012-08-01 EP claimed
JP-7247246-A None JP disclosed
CN-118406037-B Triazole derivative and preparation method and application thereof 四川师范大学 2025-02-25 CN disclosed
CN-118406037-A Triazole derivative and preparation method and application thereof 四川师范大学 2024-07-30 CN disclosed
CN-114409501-B Method for preparing propargyl alcohol compound by taking pinacol borane as hydrogen source 云南民族大学 2024-05-10 CN disclosed
WO-2023190354-A1 LAMINATED PLASTIC FILM, USE OF LAMINATED PLASTIC FILM AS RECYCLABLE RAW MATERIAL, LAMINATED PLASTIC FILM FOR RECYCLABLE RAW MATERIAL, AND METHOD FOR PRODUCING RECYCLABLE PLASTIC FILM 三菱ケミカル株式会社 2023-10-05 WO disclosed
CN-111263987-B Optical film, optical film preparation method and organic light-emitting electronic device preparation method 株式会社LG化学 2023-05-02 CN disclosed
WO-2023276648-A1 LIQUID COMPOSITION FOR SILICONE RUBBER SPHERICAL PARTICLES, SILICONE RUBBER SPHERICAL PARTICLES AND PRODUCTION METHOD THEREFOR, AND SILICONE COMPOSITE PARTICLES AND PRODUCTION METHOD THEREFOR 信越化学工業株式会社 2023-01-05 WO disclosed
WO-2022250125-A1 SILICONE COMPOSITION FOR FORMING PEELABLE CURED FILM, AND RELEASE SHEET ダウ・東レ株式会社 2022-12-01 WO disclosed
EP-0255098-B1 Novel 8-(lower alkyl) bicyclo [4.2.0] octane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1991-05-29 EP disclosed
US-4983627-A Treating atherosclerosis, thrombosis and vasospasms; anticholesterol,-secretory,-ulcer and hypotensive agents SYNTEX (U.S.A.) INC. (US) 1991-01-08 US disclosed
EP-0196617-B1 [4.2.0]bicyclooctane derivatives, process for their preparation and pharmaceutical compositions containing same SYNTEX (U.S.A.) INC. (US) 1989-05-31 EP disclosed
US-4735966-A ANTICOAGULANTS, VASODILATORS, HYPOTENSIVE AND ANTICHOLESTEROL AGENTS SYNTEX (U.S.A.) INC. (US) 1988-04-05 US disclosed
EP-0257609-A2 Novel substituted (4.2.0)Bicyclooctane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1988-03-02 EP disclosed
EP-0255098-A1 Novel 8-(lower alkyl) bicyclo [4.2.0] octane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1988-02-03 EP disclosed
US-4678805-A Novel 8-(lower alkyl)bicyclo[4.2.0]octane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1987-07-07 US disclosed
EP-0196617-A1 [4.2.0]bicyclooctane derivatives, process for their preparation and pharmaceutical compositions containing same SYNTEX (U.S.A.) INC. (US) 1986-10-08 EP disclosed
US-4608388-A Novel [4,2,0]bicyclooctane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1986-08-26 US disclosed