Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.50 |
| ▸ | HPGDS | O60760 | 2/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7977959 | 0.99 | TRPV4 (0.49) | TRPV4HPGDSCASRLMNAKDM4E | |
| SCHEMBL7991969 | 0.88 | TRPV4 (0.50) | TRPV4HPGDSCASRLMNAKDM4E | |
| SCHEMBL7988918 | 0.83 | RAB9A (0.47) | LMNAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7977729 | 0.80 | MEN1 (0.48) | HPGDSLMNAKDM4EMEN1KMT2A | |
| SCHEMBL7989677 | 0.75 | SMN1; SMN2 (0.49) | LMNAKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL7995063 | 0.73 | SMN1; SMN2 (0.47) | LMNAKDM4ECYP2D6MEN1KMT2A | |
| SCHEMBL7989365 | 0.70 | MEN1 (0.52) | KDM4EMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL13187869 | 0.69 | NPC1 (0.48) | TRPV4LMNAKDM4ECYP2D6ADORA2A | |
| SCHEMBL6707244 | 0.68 | RAB9A (0.48) | LMNAMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL15441586 | 0.67 | TRPV4 (1.00) | TRPV4KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |