Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989677 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2L3MBTL1LMNACYP1A2CYP2C9 | |
| SCHEMBL7991969 | 0.84 | TRPV4 (0.50) | SMN1; SMN2L3MBTL1LMNACYP1A2CYP2C9 | |
| SCHEMBL7987898 | 0.77 | CYP19A1 (0.56) | SMN1; SMN2L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL6707244 | 0.75 | RAB9A (0.48) | SMN1; SMN2L3MBTL1LMNACYP1A2CYP2C9 | |
| SCHEMBL7988918 | 0.75 | RAB9A (0.47) | SMN1; SMN2L3MBTL1LMNACYP1A2CYP2C9 | |
| SCHEMBL7995289 | 0.73 | TRPV4 (0.50) | LMNARAB9ATSHRNPC1MEN1 | |
| Hydrochloric Acid SCHEMBL7977959 | 0.72 | TRPV4 (0.49) | LMNARAB9ATSHRNPC1MEN1 | |
| Hydrochloric Acid SCHEMBL7989998 | 0.69 | ALDH1A1 (0.42) | SMN1; SMN2L3MBTL1LMNARAB9APOLB | |
| SCHEMBL7977710 | 0.69 | RAB9A (0.52) | LMNACYP1A2RAB9APOLBTSHR | |
| SCHEMBL7991774 | 0.69 | RAB9A (0.52) | SMN1; SMN2L3MBTL1RAB9APOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |