Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.30 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.30 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7847239 | 0.89 | KCNH2 (0.40) | KCNH2POLBALDH1A1CHRM2CHRM1 | |
| Trifluoroacetic Acid SCHEMBL7496710 | 0.85 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL8925207 | 0.82 | ALDH1A1 (0.49) | KCNH2POLBALDH1A1CHRM2CHRM1 | |
| SCHEMBL7993753 | 0.79 | KCNH2 (0.40) | KCNH2POLBALDH1A1OPRM1CACNA1F | |
| SCHEMBL7841882 | 0.78 | KCNH2 (0.52) | KCNH2POLBALDH1A1OPRM1MEN1 | |
| SCHEMBL7495327 | 0.77 | MEN1 (0.34) | KCNH2POLBALDH1A1CHRM2CHRM1 | |
| Trifluoroacetic Acid SCHEMBL7846826 | 0.75 | ADRB2 (0.40) | KCNH2ALDH1A1CHRM2 | |
| SCHEMBL7495331 | 0.72 | — | — | |
| Trifluoroacetic Acid SCHEMBL7844915 | 0.72 | KCNH2 (0.49) | KCNH2POLBALDH1A1CHRM2CHRM1 | |
| Trifluoroacetic Acid SCHEMBL8925203 | 0.70 | ALDH1A1 (0.57) | KCNH2POLBALDH1A1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288081-B1 | Use of 7-(1-aminomethyl-2-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)-quinolone carboxylic acid and naphthyridone carboxylic acid derivatives for treating Helicobacter pylori infections and the gastroduodenal diseases associated therewith | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |