Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | EIF4E | P06730 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995380 | 0.94 | CA1 (0.45) | CA1CA2KDM4ECYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL8663603 | 0.83 | CYP2D6 (0.47) | CYP1A2CYP2D6KMT2AMAPTALDH1A1 | |
| SCHEMBL3874099 | 0.80 | CA1 (0.45) | CA1CA2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL2409870 | 0.80 | TSHR (0.49) | CA1CA2KDM4EMAPTPOLB | |
| SCHEMBL8005356 | 0.79 | MAPT (0.44) | KDM4EKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8005976 | 0.78 | MAPT (0.52) | CA1CA2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL13715371 | 0.77 | CA1 (0.49) | CA1CA2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL12774551 | 0.77 | CA1 (0.66) | CA1CA2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL8818855 | 0.77 | CA12 (0.53) | CA1CA2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL2437425 | 0.76 | TSHR (0.49) | CA1CA2KDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017917-A | Guanidine derivatives | FUJISAWA PHARAMCEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0876338-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025310-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |