Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.46 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995380 | 0.85 | CA1 (0.45) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL27539635 | 0.83 | HPGD (0.50) | POLBALDH1A1HPGDADORA3CA1 | |
| SCHEMBL29788029 | 0.81 | ALDH1A1 (0.63) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL2039734 | 0.81 | ALDH1A1 (0.63) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL4602802 | 0.80 | HDAC4 (0.62) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7995531 | 0.78 | CA1 (0.50) | MAPTKMT2AMEN1POLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL8004286 | 0.78 | CYP2D6 (0.47) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL56890 | 0.77 | KDM4E (0.55) | POLBALDH1A1LMNACA1CA2 | |
| SCHEMBL2410383 | 0.77 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1HPGDLMNA | |
| SCHEMBL3508583 | 0.76 | POLB (0.55) | MAPTKMT2AMEN1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017917-A | Guanidine derivatives | FUJISAWA PHARAMCEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0876338-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025310-A1 | GUANIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |