Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984034 | 0.87 | ALOX5AP (0.47) | F10ALOX5APFEN1F2PRSS1 | |
| SCHEMBL7995555 | 0.85 | ALOX5AP (0.44) | ALOX5APFEN1F2PRSS1 | |
| SCHEMBL7995536 | 0.85 | ALOX5AP (0.48) | ALOX5APFEN1 | |
| SCHEMBL7994283 | 0.83 | F2 (0.38) | ALOX5APFEN1F2PRSS1 | |
| SCHEMBL7995479 | 0.83 | F10 (0.44) | F10SCN9AALOX5APFEN1PRSS1 | |
| SCHEMBL7995594 | 0.74 | F10 (0.42) | F10SCN9AALOX5APFEN1F2 | |
| SCHEMBL7995486 | 0.72 | ALOX5AP (0.38) | F10ALOX5APFEN1 | |
| SCHEMBL23093501 | 0.72 | PTGS2 (0.53) | F10SCN9AALOX5APFEN1 | |
| SCHEMBL7994014 | 0.71 | ALOX5AP (0.39) | F10ALOX5APFEN1 | |
| SCHEMBL6171447 | 0.70 | ALOX5AP (0.50) | F10SCN9AALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810858-A4 | BORONIC ACID AND ESTER INHIBITORS OF THROMBIN | DU PONT PHARM CO (US) | 2000-11-15 | — | — | EP | disclosed |
| EP-0810858-A2 | BORONIC ACID AND ESTER INHIBITORS OF THROMBIN | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-12-10 | — | — | EP | disclosed |
| WO-1996020689-A2 | BORONIC ACID AND ESTER INHIBITORS OF THROMBIN | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-07-11 | — | — | WO | disclosed |