Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001628 | 0.90 | GRM2 (0.41) | KMT2AMEN1CYP2D6NPC1RAB9A | |
| SCHEMBL7994851 | 0.86 | EGFR (0.33) | CYP2D6MAPTHTTLMNATYMP | |
| SCHEMBL7995736 | 0.85 | CYP1A2 (0.43) | KMT2AMEN1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL7984644 | 0.84 | TYMP (0.38) | KMT2AMEN1CYP2D6CYP2C19NPC1 | |
| SCHEMBL8001605 | 0.83 | LMNA (0.42) | KMT2ACYP2D6CYP2C19ALDH1A1POLB | |
| SCHEMBL7996140 | 0.81 | KMT2A (0.39) | KMT2AMEN1CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL7984159 | 0.81 | EGFR (0.31) | EGFR | |
| SCHEMBL7994182 | 0.81 | KMT2A (0.40) | KMT2AMEN1CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL7994293 | 0.81 | NPC1 (0.42) | KMT2AMEN1CYP2D6CYP1A2CYP2C9 | |
| SCHEMBL7984571 | 0.79 | CYP3A4 (0.43) | KMT2ACYP2D6CYP2C19SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |