Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | TYMP | P19971 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8001605 | 0.86 | LMNA (0.42) | CYP3A4CYP2D6OPRK1TYMPLMNA | |
| SCHEMBL7998431 | 0.82 | CYP3A4 (0.40) | CYP3A4CYP2D6OPRK1TYMPLMNA | |
| SCHEMBL7998436 | 0.81 | CYP3A4 (0.42) | CYP3A4CYP2D6OPRK1LMNATHRB | |
| SCHEMBL7997717 | 0.81 | NPSR1 (0.47) | CYP3A4CYP2D6OPRK1LMNAKMT2A | |
| SCHEMBL7995693 | 0.79 | KMT2A (0.38) | CYP3A4CYP2D6OPRK1TYMPLMNA | |
| SCHEMBL8002220 | 0.78 | LMNA (0.36) | CYP3A4CYP2D6OPRK1TYMPLMNA | |
| SCHEMBL8001628 | 0.76 | GRM2 (0.41) | CYP3A4CYP2D6OPRK1TYMPKMT2A | |
| SCHEMBL7994851 | 0.75 | EGFR (0.33) | CYP3A4CYP2D6OPRK1TYMPLMNA | |
| SCHEMBL7998218 | 0.74 | SLC29A1 (0.46) | CYP3A4CYP2D6OPRK1TYMPLMNA | |
| SCHEMBL7983832 | 0.74 | STING1 (0.40) | CYP3A4CYP2D6OPRK1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |