Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995693 | 0.84 | KMT2A (0.38) | TYMPOPRK1CYP3A4CYP2D6KMT2A | |
| SCHEMBL7983844 | 0.81 | ALDH1A1 (0.36) | TYMPCYP2D6NPC1RAB9APOLB | |
| SCHEMBL7997799 | 0.78 | LMNA (0.41) | OPRK1CYP3A4CYP2D6CA12CA1 | |
| SCHEMBL8001628 | 0.73 | GRM2 (0.41) | TYMPOPRK1CYP3A4CYP2D6KMT2A | |
| SCHEMBL7996137 | 0.73 | CYP11B1 (0.54) | KMT2ALMNASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8001605 | 0.72 | LMNA (0.42) | TYMPOPRK1CYP3A4CYP2D6CA12 | |
| SCHEMBL7984571 | 0.71 | CYP3A4 (0.43) | TYMPOPRK1CYP3A4CYP2D6CA12 | |
| SCHEMBL7994851 | 0.70 | EGFR (0.33) | TYMPOPRK1CYP3A4CYP2D6LMNA | |
| SCHEMBL7995736 | 0.69 | CYP1A2 (0.43) | KMT2APOLBLMNATHRBCYP2C19 | |
| SCHEMBL7998218 | 0.67 | SLC29A1 (0.46) | TYMPOPRK1CYP3A4CYP2D6CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |