Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995444 | 0.84 | TTR (0.41) | TTRLTA4HPTGS1PTGS2LOXL2 | |
| Hydrochloric Acid SCHEMBL10918619 | 0.78 | L3MBTL1 (0.56) | LTA4HMAPTBRD4 | |
| SCHEMBL3393106 | 0.78 | ATP1A1 (0.37) | CYP2D6KCNH2MAPTALDH1A1TSHR | |
| SCHEMBL30163883 | 0.78 | ATP1A1 (0.37) | CYP2D6KCNH2MAPTALDH1A1TSHR | |
| SCHEMBL7997563 | 0.78 | PTGS1 (0.43) | LTA4HPTGS1PTGS2MAPTTSHR | |
| SCHEMBL7995467 | 0.77 | ALDH1A1 (0.44) | MAPTALDH1A1TSHR | |
| SCHEMBL10335446 | 0.76 | SMN1; SMN2 (0.44) | TTRCYP2D6KCNH2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL2111356 | 0.76 | PDE10A (0.38) | CYP2D6KCNH2MAPTALDH1A1TSHR | |
| SCHEMBL6861334 | 0.75 | MAPT (0.35) | PTGS1SLC6A2CYP2D6KCNH2MAPT | |
| SCHEMBL6872706 | 0.75 | MAPT (0.38) | PTGS1SLC6A2CYP2D6KCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |