Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.62 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.62 |
| ▸ | CLK1 | P49759 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CCR6 | P51684 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.38 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257875 | 0.85 | GRM2 (0.47) | DYRK1ADYRK1BCLK1MAPTGRM2 | |
| SCHEMBL9257881 | 0.85 | GRM2 (0.47) | DYRK1ADYRK1BCLK1MAPTGRM2 | |
| SCHEMBL7992606 | 0.84 | MAPT (0.50) | DYRK1ADYRK1BCLK1MAPTCYP1A2 | |
| SCHEMBL7990444 | 0.82 | ALDH1A1 (0.52) | DYRK1ADYRK1BCLK1MAPTGRM2 | |
| SCHEMBL9252868 | 0.81 | USP18 (0.48) | DYRK1ADYRK1BCLK1MAPTMAOB | |
| SCHEMBL9252871 | 0.81 | USP18 (0.48) | DYRK1ADYRK1BCLK1MAPTMAOB | |
| SCHEMBL6059814 | 0.77 | DYRK1A (1.00) | DYRK1ADYRK1BCLK1MAPTCYP1A2 | |
| SCHEMBL9253106 | 0.72 | GRM2 (0.39) | GRM2CYP1A2PRKCA | |
| SCHEMBL9261402 | 0.71 | PRKCA (0.43) | GRM2CYP1A2CCR6PRKCA | |
| SCHEMBL9261410 | 0.71 | PRKCA (0.43) | GRM2CYP1A2CCR6PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258963-B1 | DRUGS, COSMETICS | HAARMANN & REIMER GMBH (DE) | 2001-07-10 | — | — | US | disclosed |