Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999914 | 0.90 | F10 (0.63) | F10F2ESR1ESR2 | |
| SCHEMBL8003156 | 0.84 | F10 (0.61) | F10MEN1KMT2AF2 | |
| Hydrochloric Acid SCHEMBL6896958 | 0.83 | F10 (0.61) | F10MEN1KMT2AF2 | |
| SCHEMBL7986862 | 0.82 | F10 (0.57) | F10TSHRF2 | |
| SCHEMBL7996090 | 0.82 | F10 (0.57) | F10F2 | |
| SCHEMBL1652910 | 0.81 | F10 (0.80) | F10F2 | |
| SCHEMBL7996212 | 0.81 | F10 (0.62) | F10MEN1KMT2AF2 | |
| SCHEMBL1651276 | 0.80 | F10 (0.59) | F10 | |
| SCHEMBL7074867 | 0.78 | TGM2 (0.55) | F10MEN1KMT2ATSHRF2 | |
| SCHEMBL7999726 | 0.78 | FNTA (0.43) | F10MEN1KMT2AFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |