Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.30 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.30 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21767671 | 0.83 | LSS (0.39) | LSSFAAHMGLLNAMPTALDH1A1 | |
| SCHEMBL21767675 | 0.83 | LSS (0.39) | LSSFAAHMGLLNAMPTALDH1A1 | |
| SCHEMBL30094731 | 0.82 | LSS (0.40) | LSSFAAHMGLLNAMPTALDH1A1 | |
| SCHEMBL31063417 | 0.80 | PRMT5 (0.43) | ALDH1A1 | |
| SCHEMBL31063148 | 0.80 | PRMT5 (0.43) | ALDH1A1 | |
| SCHEMBL7997019 | 0.79 | NAMPT (0.38) | LSSNAMPTALDH1A1 | |
| SCHEMBL28559014 | 0.78 | TEAD3 (0.37) | LSSFAAHNAMPTTEAD1TEAD3 | |
| SCHEMBL21784674 | 0.77 | PRMT5 (0.42) | LSSALDH1A1 | |
| SCHEMBL21780530 | 0.77 | PRMT5 (0.42) | LSSALDH1A1 | |
| SCHEMBL31063081 | 0.76 | PRMT5 (0.42) | LSSALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108507-A1 | THERAPEUTIC COMPOUNDS | MERCK & CO., INC. (US) | 2009-09-03 | — | — | WO | disclosed |