SCHEMBL799654

SCHEMBL799654

NC(=O)Cc1ccc(Cl)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.64
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
RAB9A P51151 4/20 0.55
NPC1 O15118 3/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
CTBP2 P56545 1/20 0.52
LMNA P02545 1/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
KMT2A Q03164 1/20 0.50
PIK3CA P42336 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8185829 0.98 CA2 (0.61) CA2CYP2C9CYP2C19RAB9ANPC1
Hydrochloric Acid SCHEMBL3818358 0.98 CA2 (0.61) CA2CYP2C9CYP2C19RAB9ANPC1
SCHEMBL12809543 0.94 CA2 (0.57) CA2CYP2C9CYP2C19RAB9ANPC1
SCHEMBL9157209 0.88 LTA4H (0.52) CA2L3MBTL1
SCHEMBL11290860 0.87 CA2 (0.80) CA2ALDH1A1
Trifluoroacetic Acid SCHEMBL5659578 0.87 CA2 (0.50) CA2CYP2C9CYP2C19RAB9ANPC1
SCHEMBL10923300 0.85 CA2 (0.48) CA2CYP2C9CYP2C19RAB9ANPC1
SCHEMBL1512090 0.82 CYP2C9 (0.52) CA2CYP2C9CYP2C19RAB9ANPC1
SCHEMBL17501386 0.81 CA2 (0.64) CA2LMNA
SCHEMBL9449852 0.81 CA2 (0.64) CA2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 671 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119595796-A Sampling detection method for phenacetin content 华中药业股份有限公司 2025-03-11 CN claimed
CN-118443832-A Method for detecting parachlorophenylacetamide in paracetamol vitamin C effervescent tablet 江苏和汇医药科技有限公司 2024-08-06 CN claimed
CN-118258923-A Method for detecting impurity content in aminomethyl guaifenesin compound preparation by HPLC method 四川逢春制药有限公司 2024-06-28 CN claimed
CN-114965754-B Method for detecting related substances and bacteriostat in acetaminophen tablet 陕西必康制药集团控股有限公司 2024-04-09 CN claimed
CN-115097049-A Method for determining related substances in pediatric paracetamol, atificial cow-bezoar and chlorphenamine maleate granules 广西壮族自治区食品药品检验所 2022-09-23 CN claimed
CN-115078576-A Analysis method of related substances of paracetamol dihydrocodeine tablets 陕西九州制药有限责任公司 2022-09-20 CN claimed
CN-114965754-A Method for detecting related substances and bacteriostatic agent in acetaminophen tablet 陕西必康制药集团控股有限公司 2022-08-30 CN claimed
CN-114062554-A Analysis method for simultaneously determining acetaminophen ibuprofen-related substances 山东百诺医药股份有限公司 2022-02-18 CN claimed
CN-112526017-A Method for detecting contents of various impurities in amimetu-yusu compound preparation by using HPLC (high performance liquid chromatography) method 四川逢春制药有限公司 2021-03-19 CN claimed
EP-3697791-A1 HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING HETEROCYCLIC COMPOUND, AND METHODS OF USE THEREOF JS Innopharm (Shanghai) Ltd. (CN) 2020-08-26 EP claimed
EP-1186318-A2 Combination, for treating depression and anxiety, containing a 5HT1d receptor antagonist and aCNS penetrant NK-1 receptor antagonist Pfizer Products Inc. (US) 2002-03-13 EP claimed
JP-2002501024-A 2002-01-15 JP claimed
US-20020002168-A1 Heterocyclic carboxamides HOWARD HARRY R (US) 2002-01-03 US claimed
US-20010041705-A1 Heterocyclic carboxamides HOWARD HARRY R (US) 2001-11-15 US claimed
EP-1142877-A1 2-OXOQUINOLINE COMPOUNDS AND MEDICINAL USES THEREOF JAPAN TOBACCO INC. (JP) 2001-10-10 EP claimed
US-6277852-B1 FOR TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS PFIZER INC 2001-08-21 US claimed
EP-1051176-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS Aventis Pharmaceuticals Products Inc. (US) 2000-11-15 EP claimed
EP-0957099-A2 Heterocyclic carboxamides Pfizer Products Inc. (US) 1999-11-17 EP claimed
WO-1999037304-A1 SUBSTITUTED OXOAZAHETEROCYCLYL FACTOR Xa INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-07-29 WO claimed
WO-1994024095-A1 IMMUNOSUPPRESSIVE AGENTS ABBOTT LABORATORIES (US) 1994-10-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020002168-A1 Heterocyclic carboxamides HTR1A, HTR1D, NPY1R CA2 1080/4885CYP2C9 795/4885CYP2C19 518/4885
US-20010041705-A1 Heterocyclic carboxamides HTR1A, HTR1D, NPY1R CA2 1080/4885CYP2C9 795/4885CYP2C19 518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.