Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 7/20 | 0.41 |
| ▸ | THRB | P10828 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997836 | 0.85 | TP53 (0.41) | TP53THRBALDH1A1POLBGAA | |
| SCHEMBL7994234 | 0.84 | TP53 (0.40) | TP53THRBALDH1A1POLBGAA | |
| SCHEMBL7994182 | 0.84 | KMT2A (0.40) | ALDH1A1POLBHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL7995736 | 0.83 | CYP1A2 (0.43) | TP53THRBALDH1A1POLBGAA | |
| SCHEMBL7998777 | 0.82 | GRM2 (0.45) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7994719 | 0.80 | HTR7 (0.34) | ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7994222 | 0.79 | SMN1; SMN2 (0.47) | TP53THRBALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8002275 | 0.75 | ALDH1A1 (0.49) | TP53THRBALDH1A1POLBGAA | |
| SCHEMBL7996545 | 0.71 | CYP2D6 (0.36) | — | |
| SCHEMBL7998204 | 0.71 | GRM2 (0.41) | ALDH1A1GAASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |