Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | ITK | Q08881 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12757539 | 0.88 | SCN5A (0.49) | SCN5ASCN9AITKADORA2AKCNH2 | |
| SCHEMBL1495683 | 0.88 | P2RX3 (0.46) | SCN5ASCN9AITKADORA2AKCNH2 | |
| SCHEMBL1495413 | 0.86 | NR1I2 (0.47) | SCN5ASCN9AITKADORA2ANAMPT | |
| SCHEMBL7997679 | 0.79 | WDR5 (0.43) | KDM1AHDAC1ROCK2ALDH1A1 | |
| SCHEMBL1495480 | 0.79 | P2RX3 (0.43) | SCN5ASCN9AITKKDM1AHDAC1 | |
| SCHEMBL1495429 | 0.78 | AKR1C3 (0.45) | SCN5ASCN9AITKKDM1AHDAC1 | |
| SCHEMBL2760641 | 0.78 | NR1I2 (0.46) | SCN5ASCN9AADORA2AALDH1A1 | |
| SCHEMBL12757593 | 0.77 | SCN5A (0.43) | SCN5ASCN9AITKNAMPTHDAC1 | |
| SCHEMBL1495435 | 0.77 | WDR5 (0.42) | NAMPTKDM1AHDAC1ROCK2ROCK1 | |
| SCHEMBL1495422 | 0.76 | WDR5 (0.48) | KDM1AHDAC1ALDH1A1HPGDKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110985-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |