Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996140 | 0.86 | KMT2A (0.39) | MEN1KMT2AHSP90AA1HSP90B1LMNA | |
| SCHEMBL7994931 | 0.84 | HTR7 (0.34) | HTR7KMT2AUSP2LMNAMAPK1 | |
| SCHEMBL7984007 | 0.83 | HSP90AA1 (0.38) | HTR7HSP90AA1HSP90B1USP2LMNA | |
| SCHEMBL7994719 | 0.83 | HTR7 (0.34) | HTR7USP2LMNAMAPK1 | |
| SCHEMBL7994851 | 0.83 | EGFR (0.33) | HTR7LMNAMAPK1 | |
| SCHEMBL7994234 | 0.80 | TP53 (0.40) | MEN1KMT2ALMNA | |
| SCHEMBL8001816 | 0.78 | SMN1; SMN2 (0.46) | MEN1KMT2ALMNAMAPK1NPC1 | |
| SCHEMBL7997451 | 0.75 | HSP90AA1 (0.35) | HSP90AA1HSP90B1 | |
| SCHEMBL8001769 | 0.70 | GRM2 (0.38) | MEN1KMT2ALMNAMAPK1NPC1 | |
| SCHEMBL7994182 | 0.68 | KMT2A (0.40) | MEN1KMT2ALMNAMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |