Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 10/20 | 0.35 |
| ▸ | HSP90B1 | P14625 | 10/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996140 | 0.79 | KMT2A (0.39) | HSP90AA1HSP90B1KCNH2ALDH1A1 | |
| SCHEMBL7996749 | 0.75 | HTR7 (0.33) | HSP90AA1HSP90B1 | |
| SCHEMBL7994234 | 0.74 | TP53 (0.40) | ALDH1A1 | |
| SCHEMBL14889017 | 0.63 | MAPT (0.37) | KCNH2ALDH1A1 | |
| SCHEMBL8001605 | 0.63 | LMNA (0.42) | ALDH1A1 | |
| SCHEMBL7998049 | 0.63 | ALDH1A1 (0.38) | HSP90AA1HSP90B1ALDH1A1 | |
| SCHEMBL7984571 | 0.62 | CYP3A4 (0.43) | ALDH1A1 | |
| SCHEMBL8001602 | 0.62 | ALDH1A1 (0.38) | HSP90AA1HSP90B1ALDH1A1 | |
| SCHEMBL28605374 | 0.61 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL8001769 | 0.61 | GRM2 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |