Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 8/20 | 0.66 |
| ▸ | SELE | P16581 | 2/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.64 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996846 | 1.00 | SELP (0.66) | SELPSELEPTPN1PRSS12APP | |
| SCHEMBL7995403 | 0.88 | SELP (0.65) | SELPSELEPTPN1APPADORA3 | |
| SCHEMBL7995416 | 0.88 | SELP (0.65) | SELPSELEPTPN1APPADORA3 | |
| SCHEMBL8181836 | 0.87 | SELP (0.74) | SELPSELEPTPN1APPEGFR | |
| SCHEMBL7999875 | 0.84 | SELP (0.70) | SELPSELEPTPN1APPKMT2A | |
| SCHEMBL7999883 | 0.84 | SELP (0.70) | SELPSELEPTPN1APPKMT2A | |
| SCHEMBL7999878 | 0.84 | SELP (0.70) | SELPSELEPTPN1APPKMT2A | |
| SCHEMBL7993959 | 0.83 | SELP (0.68) | SELPSELEPTPN1KMT2AADORA3 | |
| SCHEMBL7982779 | 0.83 | SELP (0.68) | SELPSELEPTPN1KMT2AADORA3 | |
| SCHEMBL7993326 | 0.80 | SELP (1.00) | SELPSELEPTPN1APPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000033836-A9 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORP (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2000033836-A1 | 5-MEMBERED HETEROCYCLES FOR THE TREATMENT OF HUMAN DISEASES INVOLVING MODULATORS OF SELECTINS | ONTOGEN CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |