Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | BAX | Q07812 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643575 | 0.82 | MEN1 (0.47) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL4797920 | 0.82 | MEN1 (0.37) | MEN1KMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL27448990 | 0.82 | L3MBTL1 (0.46) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL2904320 | 0.80 | MEN1 (0.46) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL2903343 | 0.79 | ALOX5AP (0.34) | MEN1KMT2ANPC1ALDH1A1HPGD | |
| SCHEMBL31617489 | 0.78 | LMNA (0.45) | NPC1MAPTKDM4ELMNARAB9A | |
| SCHEMBL4365311 | 0.78 | KDR (0.50) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL2906037 | 0.76 | MAPT (0.42) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL5686902 | 0.75 | DRD1 (0.50) | MEN1KMT2AESR1ESR2LTA4H | |
| SCHEMBL4795261 | 0.73 | KDM4E (0.41) | MEN1KMT2ANPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009113320-A1 | MMP INHIBITOR | 株式会社ヤクルト本社 (JP) | 2009-09-17 | — | — | WO | disclosed |