Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 3/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2900179 | 0.80 | PLAAT3 (0.38) | ALOX5APFEN1P2RX3MEN1KMT2A | |
| SCHEMBL2897541 | 0.79 | P2RX3 (0.40) | P2RX3MEN1KMT2AHTTGAA | |
| SCHEMBL1643575 | 0.79 | MEN1 (0.47) | ALOX5APFEN1MEN1KMT2ANPC1 | |
| SCHEMBL4797920 | 0.79 | MEN1 (0.37) | ALOX5APFEN1P2RX3MEN1KMT2A | |
| SCHEMBL27448990 | 0.79 | L3MBTL1 (0.46) | ALOX5APFEN1MEN1KMT2AHTT | |
| SCHEMBL7997013 | 0.79 | MEN1 (0.45) | P2RX3MEN1KMT2AHTTGAA | |
| SCHEMBL31617489 | 0.75 | LMNA (0.45) | NPC1RAB9A | |
| SCHEMBL8423836 | 0.72 | RAB9A (0.41) | ALOX5APFEN1MEN1KMT2ANPC1 | |
| SCHEMBL4795261 | 0.70 | KDM4E (0.41) | ALOX5APFEN1MEN1KMT2AHTT | |
| SCHEMBL17623900 | 0.70 | MAP4K4 (0.49) | ALOX5APFEN1ALDH1A1HPGDMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | ALOX5AP 813/4885FEN1 3016/4885P2RX3 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.