Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 1/20 | 0.38 |
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997479 | 0.65 | CTH (0.35) | CTH | |
| SCHEMBL8056179 | 0.62 | KDM4E (0.33) | CTHKDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL27697249 | 0.56 | CTH (0.35) | CTH | |
| SCHEMBL27288275 | 0.56 | POLB (0.31) | — | |
| SCHEMBL16387368 | 0.56 | — | — | |
| SCHEMBL22453898 | 0.55 | HAAO (0.32) | CTHTPMT | |
| SCHEMBL27723749 | 0.54 | TSHR (0.41) | KDM4EGAA | |
| SCHEMBL10964095 | 0.54 | ALOX15 (0.36) | CTHKDM4EKMT2AHPGDHSD17B10 | |
| SCHEMBL5052149 | 0.53 | TPMT (0.56) | TPMTKDM4EHPGDHSD17B10NOTUM | |
| SCHEMBL235710 | 0.52 | KDM4E (0.54) | TPMTKDM4EKMT2AGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0998946-A1 | Non-porphyrin compound for use as a diagnosticum and/or pharmaceutical | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-05-10 | — | — | EP | claimed |
| WO-2000009169-A1 | NON-PORPHYRIN COMPOUND FOR USE AS A DIAGNOSTICUM AND/OR PHARMACEUTICAL | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2000-02-24 | — | — | WO | claimed |