Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7904260 | 0.76 | PTGES2 (0.47) | PTGES2LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL7904258 | 0.76 | PTGES2 (0.47) | PTGES2LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL8000279 | 0.75 | KMT2A (0.43) | LMNAMAPTALDH1A1L3MBTL1PPARG | |
| SCHEMBL7905094 | 0.73 | PTGES2 (0.50) | PTGES2LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL7905095 | 0.73 | PTGES2 (0.50) | PTGES2LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL22735170 | 0.73 | PPARG (0.71) | PTGES2LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL22735168 | 0.73 | PPARG (0.71) | PTGES2LMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL11486259 | 0.72 | ALDH1A1 (0.59) | LMNAMAPTALDH1A1L3MBTL1SNCA | |
| SCHEMBL700236 | 0.72 | ALDH1A1 (0.59) | LMNAMAPTALDH1A1L3MBTL1SNCA | |
| SCHEMBL700237 | 0.72 | ALDH1A1 (0.59) | LMNAMAPTALDH1A1L3MBTL1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120783-A1 | HIGH AFFINITY INHIBITORS OF HEPATITIS C VIRUS NS3/4A PROTEASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2009-10-01 | — | — | WO | disclosed |