Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988652 | 0.85 | PPARG (0.44) | KMT2AMAPTPOLBCYP3A4PARP1 | |
| SCHEMBL7988661 | 0.82 | PPARG (0.49) | KMT2AMAPTTSHRL3MBTL1CYP1B1 | |
| SCHEMBL1240823 | 0.77 | CA2 (0.49) | KMT2AMAPTPOLBCYP3A4PARP1 | |
| SCHEMBL7187617 | 0.75 | MAPT (0.62) | KMT2AMAPTPOLBCYP3A4PARP1 | |
| SCHEMBL4156173 | 0.75 | MAPT (0.62) | KMT2AMAPTPOLBCYP3A4PARP1 | |
| SCHEMBL16131295 | 0.75 | MAPT (0.62) | KMT2AMAPTPOLBCYP3A4PARP1 | |
| SCHEMBL7997495 | 0.75 | PTGES2 (0.44) | MAPTTSHRL3MBTL1PPARGLMNA | |
| SCHEMBL7998748 | 0.74 | CYP19A1 (0.41) | KMT2AMAPTPOLBSMN1; SMN2PPARG | |
| SCHEMBL8004163 | 0.72 | TSHR (0.42) | KMT2AMAPTPOLBTSHRCYP2C19 | |
| SCHEMBL8279346 | 0.70 | PPARG (0.39) | KMT2AMAPTPOLBHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120783-A1 | HIGH AFFINITY INHIBITORS OF HEPATITIS C VIRUS NS3/4A PROTEASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2009-10-01 | — | — | WO | disclosed |