Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HTR1B | P28222 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212429 | 0.90 | HTR1B (0.58) | KDM4EHPGDSMN1; SMN2HTR1BMAPK1 | |
| SCHEMBL27946664 | 0.87 | KDM4E (0.57) | KDM4EHPGDSMN1; SMN2MAPK1MAPT | |
| SCHEMBL17445915 | 0.85 | KDM4E (0.51) | KDM4EHPGDMAPK1TP53MAPT | |
| SCHEMBL10458645 | 0.84 | KCNH2 (0.48) | KDM4EHPGDSMN1; SMN2HTR1BMAPK1 | |
| SCHEMBL19632809 | 0.83 | KDM4E (0.68) | KDM4EHPGDSMN1; SMN2HTR1BMAPK1 | |
| SCHEMBL7873203 | 0.83 | IDO1 (0.53) | KDM4EHPGDSMN1; SMN2HTR1BMAPK1 | |
| SCHEMBL2921540 | 0.83 | KDM4E (0.43) | KDM4EHPGDSMN1; SMN2HTR1BMAPK1 | |
| SCHEMBL7997520 | 0.82 | HTR1B (0.50) | KDM4EHPGDSMN1; SMN2HTR1BMAPK1 | |
| Hydrochloric Acid SCHEMBL25375445 | 0.82 | KDM4E (0.72) | KDM4EHPGDSMN1; SMN2HTR1BMAPK1 | |
| SCHEMBL31050988 | 0.80 | KDM4E (0.95) | KDM4EHPGDSMN1; SMN2HTR1BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041044-A1 | PROCESS FOR THE PREPARATION OF CARVEDILOL AND ITS ENANTIOMERS | ZACH SYSTEM S.P.A. (IT) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041044-A1 | PROCESS FOR THE PREPARATION OF CARVEDILOL AND ITS ENANTIOMERS | ADRB1, ADRB2, ADRA1A | KDM4E 2266/4885HPGD 1220/4885SMN1; SMN2 2872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.