Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL906050 | 0.75 | HTR2C (0.66) | LMNAPMP22NPSR1GFERHDAC1 | |
| SCHEMBL8067706 | 0.74 | DRD1 (0.50) | HDAC1HDAC6NOTUMHTR2AHTR2C | |
| SCHEMBL23489361 | 0.74 | MAPT (0.50) | HDAC1HDAC6BIRC2NOTUMCYP3A4 | |
| Hydrochloric Acid SCHEMBL7674594 | 0.74 | HTR2C (0.64) | LMNAPMP22NPSR1GFERHDAC1 | |
| SCHEMBL7679546 | 0.74 | LMNA (0.64) | LMNAPMP22NPSR1GFERHDAC1 | |
| SCHEMBL7673512 | 0.74 | HTR2A (0.61) | LMNAPMP22NPSR1GFERHDAC1 | |
| SCHEMBL1770605 | 0.72 | MTNR1A (0.55) | HDAC1HDAC6NOTUMHTR2CMTNR1A | |
| SCHEMBL7041539 | 0.72 | HSD17B10 (0.50) | LMNAHDAC1HDAC6NOTUMMTNR1A | |
| Ammonia Solution, Strong SCHEMBL906052 | 0.72 | DRD1 (0.50) | HDAC1HDAC6NOTUMRORCDRD2 | |
| Hydrochloric Acid SCHEMBL7840936 | 0.71 | DRD1 (0.47) | HDAC1HDAC6DRD2DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | disclosed |