Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 9/20 | 0.39 |
| ▸ | ACHE | P22303 | 8/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7997594 | 1.00 | CA12 (0.40) | CA12CA9SMN1; SMN2HTR1AHTR2C | |
| SCHEMBL8000909 | 0.90 | BCHE (0.43) | CA12CA9SMN1; SMN2HTR1AHTR2C | |
| SCHEMBL8000910 | 0.90 | BCHE (0.43) | CA12CA9SMN1; SMN2HTR1AHTR2C | |
| SCHEMBL7988120 | 0.87 | L3MBTL1 (0.43) | CA12CA9MEN1KMT2ABCHE | |
| SCHEMBL7988117 | 0.87 | L3MBTL1 (0.43) | CA12CA9MEN1KMT2ABCHE | |
| SCHEMBL8000654 | 0.85 | CA12 (0.40) | CA12CA9SMN1; SMN2HTR1AHTR2C | |
| SCHEMBL8000652 | 0.85 | CA12 (0.40) | CA12CA9SMN1; SMN2HTR1AHTR2C | |
| SCHEMBL8004133 | 0.84 | MMP1 (0.43) | CA12CA9MEN1KMT2ABCHE | |
| SCHEMBL7988397 | 0.84 | MMP1 (0.43) | CA12CA9MEN1KMT2ABCHE | |
| SCHEMBL8000658 | 0.84 | CA12 (0.40) | CA12CA9SMN1; SMN2HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |