Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004133 | 1.00 | MMP1 (0.43) | MMP1MMP2MMP9EGFRMCHR1 | |
| SCHEMBL7988117 | 0.93 | L3MBTL1 (0.43) | EGFRMCHR1BCHEL3MBTL1DHFR | |
| SCHEMBL7988120 | 0.93 | L3MBTL1 (0.43) | EGFRMCHR1BCHEL3MBTL1DHFR | |
| SCHEMBL7988456 | 0.89 | L3MBTL1 (0.45) | MMP1MMP2MMP9EGFRMCHR1 | |
| SCHEMBL7988459 | 0.89 | L3MBTL1 (0.45) | MMP1MMP2MMP9EGFRMCHR1 | |
| SCHEMBL8004109 | 0.88 | DHFR (0.41) | MMP1MMP2MMP9EGFRMCHR1 | |
| SCHEMBL8004114 | 0.88 | DHFR (0.41) | MMP1MMP2MMP9EGFRMCHR1 | |
| SCHEMBL8001387 | 0.86 | L3MBTL1 (0.46) | MMP1MMP2MMP9EGFRMCHR1 | |
| SCHEMBL8001392 | 0.86 | L3MBTL1 (0.46) | MMP1MMP2MMP9EGFRMCHR1 | |
| SCHEMBL7998863 | 0.86 | PTGES (0.39) | MMP1MMP2MMP9EGFRMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114352-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |