Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996149 | 0.92 | HCRTR1 (0.46) | L3MBTL1LMNATP53MAPTPKM | |
| SCHEMBL7986759 | 0.91 | MAPT (0.42) | L3MBTL1LMNATP53MAPTSMN1; SMN2 | |
| SCHEMBL7996072 | 0.91 | LMNA (0.46) | CA12CA1CA2CA9LMNA | |
| SCHEMBL7996075 | 0.86 | F10 (0.48) | CA12CA1CA2CA9LMNA | |
| SCHEMBL7069980 | 0.86 | TSHR (0.54) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL7999726 | 0.86 | FNTA (0.43) | LMNATP53MAPTSMN1; SMN2TSHR | |
| SCHEMBL7996216 | 0.85 | LMNA (0.46) | CA12CA1CA2CA9LMNA | |
| SCHEMBL8003134 | 0.85 | MAPT (0.48) | L3MBTL1LMNATP53MAPTSMN1; SMN2 | |
| SCHEMBL7996147 | 0.85 | LMNA (0.42) | LMNATP53MAPTSMN1; SMN2PKM | |
| SCHEMBL7997760 | 0.83 | MAPT (0.47) | L3MBTL1LMNATP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |