Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 7/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986640 | 0.91 | HCRTR1 (0.45) | FNTAFNTBMAPTTP53MEN1 | |
| SCHEMBL7997639 | 0.86 | L3MBTL1 (0.45) | MAPTTP53MEN1KMT2ALMNA | |
| SCHEMBL7996072 | 0.85 | LMNA (0.46) | MAPTTP53MEN1KMT2ALMNA | |
| SCHEMBL7996216 | 0.83 | LMNA (0.46) | MAPTTP53LMNATHRBF10 | |
| SCHEMBL8000074 | 0.82 | LMNA (0.42) | MAPTLMNATSHRTHRBF10 | |
| SCHEMBL7996149 | 0.80 | HCRTR1 (0.46) | MAPTTP53LMNATHRBALDH1A1 | |
| SCHEMBL7070017 | 0.80 | DGAT1 (0.50) | MAPTMEN1KMT2ALMNATSHR | |
| SCHEMBL7996147 | 0.79 | LMNA (0.42) | MAPTTP53LMNATHRBF10 | |
| SCHEMBL7996075 | 0.79 | F10 (0.48) | MAPTTP53LMNAF10ALDH1A1 | |
| SCHEMBL7986759 | 0.78 | MAPT (0.42) | MAPTTP53LMNATSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008005-A2 | PIPERAZINONE DERIVATIVES | MERCK PATENT GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |