Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 5/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27524962 | 0.91 | HTR2A (0.46) | KMOACLYOXER1NPY5RAR | |
| SCHEMBL8959588 | 0.91 | HTR2A (0.46) | KMOACLYOXER1NPY5RAR | |
| SCHEMBL27528051 | 0.87 | HTR2A (0.45) | KMOHTR7MCL1HTR2AHTR2C | |
| SCHEMBL8959581 | 0.87 | HTR2A (0.45) | KMOHTR7MCL1HTR2AHTR2C | |
| SCHEMBL8959562 | 0.86 | HTR2C (0.46) | HTR7PPARGNPY5RARHTR2A | |
| SCHEMBL27356666 | 0.86 | HTR2C (0.46) | HTR7PPARGNPY5RARHTR2A | |
| SCHEMBL8959864 | 0.83 | HTR2A (0.49) | KMOARHTR2AHTR2C | |
| SCHEMBL8959561 | 0.83 | HTR2A (0.49) | KMOARHTR2AHTR2C | |
| SCHEMBL8959713 | 0.83 | HTR2A (0.49) | KMOARHTR2AHTR2C | |
| SCHEMBL27363223 | 0.83 | HTR2A (0.49) | KMOARHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040183-A1 | 1-AMINOALKYL-1H-INDOLES FOR TREATING GLAUCOMA | ALCON UNIVERSAL LTD. (CH) | 2001-06-07 | — | — | WO | disclosed |